By adding a proprietary IonRail collision cell, and another high precision quadrupole (serving as a mass filter Q3), your 5973N/5975 is easily upgraded.

Software is original Agilent MSD Chemstation with inserted macros for Q3 Autotune and other MS/MS control functions. By keeping the original ion source, the true hyperbolic quadrupole and the highly sensitive HED detector provides true MS-MS.



The first quadrupole mass filter (Q1) pre-selects a precursor ion (“parent ion”) which is fragmented by collision with an inert gas in the RF-only collision cell (q2).
The resulting product ions (“daughter ion”) are subsequently selected by the third quadrupole (Q3) mass filter.

Multiple Reaction Monitoring (MRM) is the most sensitive and selective technique to overcome matrix-related problems and further quantify target compounds in the most demanding matrices.