Troubleshooting Process Chart
– Probable Instrument Fault
– Correct / Change Set-up & Re-run Analysis
– Probable Methodology Fault
– Leak in System – Pump Fault
– Detector Fault or Injector Fault
– Pump Fault or Column Compartment Fault
– Autosampler Fault
– Improve Method
– High Back Pressure Issues
– Run a Known Method on the System
– Look for Differences Between Systems
– Probable Instrument Fault
– Correct / Change Set-up & Re-run Analysis
– Probable Methodology Fault
– Leak in System – Pump Fault
– Detector Fault or Injector Fault
– Pump Fault or Column Compartment Fault
– Autosampler Fault
– Improve Method
– High Back Pressure Issues
– Run a Known Method on the System
– Look for Differences Between Systems
Welcome to the home section of Jaytee’s engineer’s guide to HPLC fault diagnosis.
