This 6490 Triple Quadrupole LC/MS has been fully cleaned, refurbished and configured in our labs here in Kent, UK. Featuring Agilent’s iFunnel Technology, it combines unique Agilent Jet Stream technology with a hexabore capillary sampling array and dual-stage ion funnel assembly to increase ion sampling and transmission from the AJS spray plume into the 6490 ion focusing optics. It has been tuned and calibrated with excellent data - please see PDF reports above.

It comes with an Agilent MS 120 roughing pump which offers the added benefit of being extremely quiet when operating.

The system delivers:

• 10 X increase in sensitivity
• Up to six orders of linear dynamic range
• Robust performance and operation
• Femtomole sensitivity for the most challenging applications

For full details of the technologies involved, please refer to the Agilent 6490 iFunnel OEM Brochure PDF linked above.

Agilent 6490 iFunnel LC-MS/MS Specification

• Electrospray ESI+ MS/MS sensitivity: 1 pg of on the transition m/z 609 to 195 / Signal-to-noise ratio > 60,000:1
• Electrospray ESI- MS/MS sensitivity: 1 pg of on the transition m/z 321 to 152 / Signal-to-noise ratio > 50,000:1
• Mass Range (m/z) : 5-1400 amu
• Polarity switching : Switch from positive ion mode to negative ion mode in 20 ms
• Mass resolution : 0.4 amu
• Mass accuracy : 0.01% or 0.1 Da
• Mass stability : < 0.1 u in 48 h
• Dynamic range : > 6.0 x 10⁶
• Scan rate : MS scan, MS/MS product ion scan, MRM, MS/MS neutral loss/gain scan and precursor ion scan, SIM, tMRM
• Minimum MRM dwell time : 1 ms
• MRM transitions: 500 per second, >40,000 MRMs possible in a method
• Collision cell : High-pressure, hexapole with linear acceleration collision cell
• Cross-talk : None detectable
• Single point of control : Single-point data system method capability with full control of Agilent 1200 Series HPLC systems and 6490A Triple Quadrupole LC/MS System
• Time Programming :
  • Polarity change in time segment
  • Continuous polarity change during entire method
  • Scan and SIM or MRM (plus other modes of data collection)
  • Dynamic MRM aligns MRMs with compound retention time
  • Solvent divert through calibrant delivery valve
  • Electrospray (ESI)
  • Multimode source (simultaneous ESI and APCI)
• Autotune : Automated optimization of ion optics and mass axis calibration with Agilent Jet stream Ion focusing technology
• Solvent declustering : Agilent Jet Stream Ion Focusing Technology and Countercurrent gas
• Detector : High-energy conversion dynode and high-gain electron multiplier horn
• Vacuum system : Two turbomolecular pumps with two mechanical pump

For full details of the technologies involved, please refer to the Agilent 6490 Specification PDF linked above.

1290 System Options

• 1290 Infinity G1316C Infinity TCC Column Oven
• Gerstel 1290 Infinity G4278A LC HTC Autosampler
• 1290 G4226A Well Plate Autosampler
• 1290 G4220A Binary Pump
• Bottle tray

System Includes

• Agilent 6490 iFunnel LC/MS-MS
• Agilent 1290 HTC UHPLC system
• Agilent MS 120 Roughing Pump
• Nitrogen Gas Filters
• PC inc TFT running MassHunter version B.08.02
• New Samsung Printer
• UK Installation - enquire for EU
• 12 month Warranty (UK - enquire for EU)

Available for demo (in lab or online) now - please enquire below.