Ref: st5861


This Agilent 6530 Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) LC/MS
system features Agilent Jet Stream Thermal Focusing technology for significantly improved sensitivity. In addition, it comes complete with enhanced MassHunter Workstation software for superior data mining and analysis capabilities. The system delivers exceptional sensitivity, excellent mass accuracy, fast data acquisition, and streamlined qualitative and quantitative analyses.

6530 Q-ToF LC/MS From Agilent

This 6530 Q-TOF platform is ideally suited for accurate-mass analyses of the complex samples encountered in today’s most demanding applications. It has been designed to provide superior data quality and advanced analytical capabilities for profiling, identifying, characterising, and quantifying low molecular-weight compounds and biomolecules with confidence.

Full MS spectra followed by MS/MS or All Ions acquisition make this instrument suitable for applications in the pharmaceutical industry as well as life sciences and governmental agencies. Accurate mass spectrometry enables you to gain more confidence in your analysis compared to unit resolution instrumentation.

Please see the tune and calibration data linked above.

Exceptional Mass Accuracy, Sensitivity, and Speed

Agilent True Hi-Def TOF technology, a key feature of this sytem, delivers outstanding Q-TOF performance characteristics without any performance compromises.

    • Sub 1-ppm mass accuracy improves confidence and reduces false positives
    • Powerful Agilent Jet Stream source enables you to uncover low level components
    • > 20,000 mass resolution distinguishes target analytes from interferences
    • Up to 5 orders of in-spectrum dynamic range improves detection of trace level targets in the presence of high-abundance compounds
    • High femtogram sensitivity enables identification of very low-abundance compounds
    • Fast data acquisition rates of up to 40 spectra/second ensure maximum compatibility with fast LC and high-throughput methods
    • Untargeted screening and quantitation using Agilent’s All Ions MS/MS technique
    • Powerful MassHunter software providing profiling, characterizing, identifying, and quantifying compounds in complex mixtures via high-definition MS and MS/MS
    • Wide mass range to 20,000 m/z

Read more about the performance of this system here:

Agilent 6530 Q-ToF LC-MS/MS Specification

  • In-spectra Dynamic Range: 5 orders
  • Ion Source: Dual-AJS (option of ESI or MultiMode)
  • MS Acquisition Rate: 50 spectra/second
  • MS Mass Accuracy (positive): <2 ppm RMS
  • MS Sensitivity (positive): S/N (RMS) > 200:1. Measured with 1pg res/pine on column
  • MS/MS Acquisition Rate: 50 spectra/second
  • MS/MS Mass Accuracy (positive): <3 ppm RMS
  • MS/MS Sensitivity (positive): S/N (RMS) > 500:1. Measured with 1pg reserpine on column
  • Polarity Switching Duty Cycle: 1 s
  • Quad Resolution (FWHM): 1.3 Da (autotune)
  • Quadrupole Isolation Mass Range: m/z 20-4000
  • TOF Mass Range: m/z 20-20,000
  • TOF Mass Resolution (FWHM): > 10,000 at m/z 118 independent of acquisition rate, > 20,000 at m/z 1522 independent of acquisition rate
  • Temperature stability : <1 ppm / 3°C

1290 System Options

  • 1290 Infinity G1316C Infinity TCC Column Oven
  • Gerstel 1290 Infinity G4278A LC HTC Autosampler
  • 1290 G4226A Well Plate Autosampler
  • 1290 G4220A Binary Pump
  • Bottle tray

System Includes

  • Agilent 6530 Q-ToF LC/MS-MS
  • Agilent 1290 UHPLC system
  • Agilent MS 40+ Roughing Pump
  • Gas Filters
  • PC inc TFT running MassHunter version B.08.02
  • New Printer
  • UK Installation - enquire for EU
  • 12 month Warranty (UK - enquire for EU)
  • Method Development

Available for demo (in lab or online) now - please enquire below.


  • System - specification as outlined in the main description
  • Sample testing - supply your compound(s) and our method development expert will provide the results for instrument assessment
  • Demonstration of capability at our lab in Kent, UK
  • Operational Data, Performance Data
  • Full service report
  • System Installation by our in-house MS Engineer (enquire if outside the UK)

Optional Extras

  • Water re-circulator
  • Syringe pump - New or reconditioned
  • Nitrogen Generator - New or reconditioned
  • Air Purifier - from CLAIND
  • Air Compressor - from CLAIND
  • Maintenance Agreements / Calibration - As the UK's biggest independent service provider of LC/GC instrumentation, we offer 4 levels of cover. Details here...


Jaytee Biosciences Ltd provide a 12 month on-site warranty (UK), effective from the date of installation.

Note: Our warranty terms quoted for this system apply to mainland UK customers. For clients outside of this locale, please enquire at point of sale.

All warranty repairs will be attended on-site however Jaytee Biosciences reserve the right to return the instrument to base for further troubleshooting if required.


  • Capillaries
  • Tubing
  • Vacuum Pump Oil
  • Exhaust Filters
  • Air Filters
  • PCs and Monitors
  • LC/GC Column Fittings
  • Electron Multipliers

Any other parts where cause of failure can be traced to customer error, neglect or accidental damage.

If you have any further queries or questions regarding warranty, please do not hesitate to contact us below.