Ref: st5052


This refurbished Waters® ACQUITY® TQD UPLC-MS/MS system includes an advanced bench top tandem quadrupole mass detector. It is ideally suited for a wide range of qualitative and quantitative applications and includes IntelliStart™ Technology, for automated system optimization and status monitoring, ensuring that the highest quality data is routinely available to users of all level.

st5052 TQD LC-MS/MS from Waters


API source: High performance ZSpray™ dual-orthogonal - ESI probe.

Ionization modes: Vacuum isolation valve, Tool free access to customer serviceable elements, Plug and play probes, De-clustering cone gas, Software control of gas flows and heating elements.

Ion source transfer optics: High efficiency hexapole ion guide.

Mass analyzer: Two high resolution quadrupole analyzers (MS1/MS2), plus prefilters to maximize resolution and transmission while preventing contamination of the main analyzers.

Collision cell: T-Wave™ 1 enabled for optimal MS/MS performance at high data acquisition rates Software programmable gas control.

Detector: Low noise, off axis, long life photomultiplier detector, Digital dynamic range up to 4 x 106.

Vacuum system: Single, split-flow air-cooled vacuum turbomolecular pump evacuating the source and analyzer, One rotary backing pump.


Acquisition modes: Full scan MS, Product ion scan, Precursor ion scan, Constant neutral loss, Selected Ion Recording (SIR), Multiple Reaction Monitoring (MRM)

Acquisition modes: Full scan MS, Product ion scan, Precursor ion scan, Constant neutral loss, Selected Ion Recording (SIR), Multiple Reaction Monitoring (MRM)

Survey scan modes: Full scan MS triggered product ion scan

Mass range: 2 to 2048 m/z

Scan speed: Up to 10,000 Da/s

Examples of achievable acquisition rates: 10 scans per second (m/z 100 to 1000), 20 scans per second (m/z 50 to 500)

Mass stability: Mass drift is <0.1 Da over a 24 hour period

Linearity of response: The linearity of response relative to sample concentration for a specified compound is five orders of magnitude from the limit of detection

Polarity switching time: 20 ms to switch between positive and negative ion modes

MRM acquisition rate: Minimum dwell time of 3 ms per MRM channel

Inter-channel cross talk: The inter-channel cross talk between two MRM transitions, acquired using an MRM dwell time of 10 ms and an inter-channel delay time of 10 ms, will be less than 0.02%.

Number of MRM channels: Up to 16,384 MRM channels (512 functions, 32 channels per function) can be monitored in a single acquisition; up to 1024 MRM channels when operating in GLP/secure mode (32 functions, 32 channels per function).

Mass resolution: Automatically adjusted (IntelliStart) to desired resolution; The valley between the 2034.63 Da and 2035.63 Da peaks is <12% of the average height of the two peaks.

MRM sensitivity (ESI+): A 1 pg on-column injection of reserpine will give a chromatographic signal-to-noise, greater than 2,000:1 (Gradient separation, LC mobile phase flow rate of 0.8 mL/min, MRM transition m/z 609 > 195).

MRM sensitivity (ESI-): A five pg loop injection of chloramphenicol, with a mobile phase flow rate of 200 µL/min will give a chromatographic signal-to-noise for the transition 321 >152 m/z greater than 180:1.

See the Waters Specification Sheet


  • Waters Acquity TQ LC-MS/MS
  • Waters Acquity Binary Solvent Manager
  • Waters Acquity Sample Manager
  • Waters Acquity Column Manager
  • Waters Acquity Bottle Tray
  • PC running both MassLynx 4.1 software and OpenLynx with Open Access Login
  • New Sumsung Printer
  • Edwards E2M28 Roughing Pump
  • Installation & warranty (as denoted above)
  • Option to include Sample Organiser - please enquire
  • *PC Provided with MassLynx software installed. Note: we are unable to transfer licences therefore software licence purchase may be required from the manufacturer.


  • System - specification as outlined in the main description
  • Sample testing - supply your compound(s) and our method development expert will provide the results for instrument assessment
  • Demonstration of capability at our lab in Kent, UK
  • Operational Data, Performance Data
  • Full service report
  • System Installation by our in-house MS Engineer (enquire if outside the UK)

Optional Extras

  • Water re-circulator
  • Syringe pump - New or reconditioned
  • Nitrogen Generator - New or reconditioned
  • Air Purifier - from CLAIND
  • Air Compressor - from CLAIND
  • Maintenance Agreements / Calibration - As the UK's biggest independent service provider of LC/GC instrumentation, we offer 4 levels of cover. Details here...
  • On-site Training - Both system overview and software familiarisation
  • Extended Warranty - we know the quality of our workmanship and hold stock of spare parts, so please enquire if you require a longer warranty period.
  • Method Development - Our in-house method development specialist has had over 40 years experience in developing methods for one of the world's largest multi-nationals. Please enquire if you require assistance in developing your methods


Jaytee Biosciences Ltd provide a 12 month on-site warranty (UK), effective from the date of installation.

Note: Our warranty terms quoted for this system apply to mainland UK customers. For clients outside of this locale, please enquire at point of sale.

All warranty repairs will be attended on-site however Jaytee Biosciences reserve the right to return the instrument to base for further troubleshooting if required.


  • Capillaries
  • Tubing
  • Vacuum Pump Oil
  • Exhaust Filters
  • Air Filters
  • PCs and Monitors
  • LC/GC Column Fittings
  • Electron Multipliers

Any other parts where cause of failure can be traced to customer error, neglect or accidental damage.

If you have any further queries or questions regarding warranty, please do not hesitate to contact us below.