Troubleshooting Process Chart
- Probable Instrument Fault
- Correct / Change Set-up & Re-run Analysis
- Probable Methodology Fault
- Leak in System - Pump Fault
- Detector Fault or Injector Fault
- Pump Fault or Column Compartment Fault
- Autosampler Fault
- Improve Method
- High Back Pressure Issues
- Run a Known Method on the System
- Look for Differences Between Systems
- Probable Instrument Fault
- Correct / Change Set-up & Re-run Analysis
- Probable Methodology Fault
- Leak in System - Pump Fault
- Detector Fault or Injector Fault
- Pump Fault or Column Compartment Fault
- Autosampler Fault
- Improve Method
- High Back Pressure Issues
- Run a Known Method on the System
- Look for Differences Between Systems
Autosampler Fault
Poor area reproducibility is caused by varying amounts of sample being injected.
Possible causes of failure:
- Worn syringe
- Sample carryover (needle seat)
- Metering device
- Faulty / worn switching valve
- Leaks inside the autosampler (e.g. Alliance autosampler leaks are not always immediately apparent)
- Seal leaks – some are more visible than others
- Leaks on the sampling side do not always show pressure changes
