Troubleshooting Process Chart
- Probable Instrument Fault
- Correct / Change Set-up & Re-run Analysis
- Probable Methodology Fault
- Leak in System - Pump Fault
- Detector Fault or Injector Fault
- Pump Fault or Column Compartment Fault
- Autosampler Fault
- Improve Method
- High Back Pressure Issues
- Run a Known Method on the System
- Look for Differences Between Systems
- Probable Instrument Fault
- Correct / Change Set-up & Re-run Analysis
- Probable Methodology Fault
- Leak in System - Pump Fault
- Detector Fault or Injector Fault
- Pump Fault or Column Compartment Fault
- Autosampler Fault
- Improve Method
- High Back Pressure Issues
- Run a Known Method on the System
- Look for Differences Between Systems
Look for Differences Between Systems
We mean:
- Is it the same make?
- Is it the same model (exactly)?
- Has it got the same configuration?
For example:
- If one has a quaternary and one has a binary pump, the gradient profile may be different as they use low and high pressure mixing respectively.
- DAD vs VWD – both use UV detection but sensitivity will be different.
- Syringe vs Metering Drive
- Data capture rate setting on software.
- Tubing connecting components can be a crucial part of the system.
Any differences can/will have an effect on the chrmoatography.
