Troubleshooting Process Chart
- Probable Instrument Fault
- Correct / Change Set-up & Re-run Analysis
- Probable Methodology Fault
- Leak in System - Pump Fault
- Detector Fault or Injector Fault
- Pump Fault or Column Compartment Fault
- Autosampler Fault
- Improve Method
- High Back Pressure Issues
- Run a Known Method on the System
- Look for Differences Between Systems
- Probable Instrument Fault
- Correct / Change Set-up & Re-run Analysis
- Probable Methodology Fault
- Leak in System - Pump Fault
- Detector Fault or Injector Fault
- Pump Fault or Column Compartment Fault
- Autosampler Fault
- Improve Method
- High Back Pressure Issues
- Run a Known Method on the System
- Look for Differences Between Systems
Step 4 -Question the instrument
Are there any indications that the instrument is not working correctly?
- Look for tell tale signs (buffer deposits around the pump head)
- Check the system logs to determine areas of poor performance (eg. lamp hours)
- Does the analytical data indicate the system is repeatable? (most systems should achieve area and retention time epeatability <1% RSD)
- What does the baseline look like?
- Investigation tests.
- Run reproducibility injections using known method, column etc.
- Is the pressure normal?
